Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

[ri'septiv]
《二十二》讲述的是22名慰安妇的故事,是中国首部票房超过1亿元的纪录片。
他编写出的第一款软件是个音频播放器,可以播放他偶像史蒂夫?乔布斯(Steve Jobs)演讲的音频片段,而音频来自一个乔布斯的传记,内容没有经过授权。如今达洛伊西奥笑着回忆道,软件因为音频受版权保护、性能不流畅、过于简单之类的各种原因,被苹果拒绝了。他早期设计的另外一个应用软件能让用户触摸一张木头的图片时发出敲击的声音。第三个应用则将智能手机的屏幕变成一个锻炼手指的跑步机,这一次,软件第一天便赚了120美元。
Salary three years after graduation and salary increase are the main criteria, each accounting for 20 per cent of the ranking’s weight. Most schools in the top 25 score well on at least one of these criteria. The top 10 schools would mostly also rank in the first 10 if salaries and their increases were excluded. The only exceptions are Nanyang Business School and China Europe International Business School, both underperforming in the doctoral and research ranks.
据高部长称,在“十三五”计划期间,中国在与“一带一路”的国家形成优势互补的跨国产业链、价值链的同时,还将持续大力改善投资环境,充分挖掘市场潜力。
SplashData公司建议,使用榜单上出现的密码的用户和公司赶快修改自己的密码。SplashData公司警告称,用数字代替字母的常见密码,像“dr4mat1c”,也很容易遭到破解,因为现在密码入侵者的科技手段也越来越高端了。
Agents and investment institutions are now flooding the sector, causing additional changes to the platforms in the world's second-largest economy, the report said.
[ju:'ni:k]
These artificial ears will be a huge benefit to those who suffer injuries or who have microtia, a condition that keeps the ears from ever developing.
张景岫说:“学生本身并不适合创业。”他补充说道,职业院校的学生比大学生更渴望自主创业。
节目14 歌曲《报喜》,陈慧琳
他补充说道:“我很兴奋能有机会重返中国,并享受这个国家的文化以及把NBA现场比赛的激动直接带给中国球迷。”
喜剧类最佳男演员:杰佛里?塔博(Jeffrey Tambor),《透明家庭》(Transparent)
3.7 加大生态环境保护治理力度
It is based on a survey of business schools and another of their alumni who graduated in 2013.
China is now home to over 80,000 trade markets and total retail sales of consumer goods would reach 30 trillion yuan this year with consumption contributing to about 60 percent of total GDP growth, Gao said.
The Death Proof star's early success was on the independent film circuit. But then she met Harvey Weinstein in a hotel room and it is there that she alleges he raped her.
尽管此次维密秀备受期待,但似乎该内衣品牌在中国的首秀并没有完全按计划进行。
In year-on-year terms prices rose in 65 cities and fell in five.
Kim, it's so simple and entry-level Finishing School stuff: keep knees and ankles together and swivel.
单词benefit 联想记忆:
"According to our survey last year, only 0.6 to 0.7 percent of students at universities were thinking about starting their own companies. The number among vocational school students was as high as 2.2 percent. However, the idea of vocational students starting businesses is related more to creating jobs for themselves, and the majority of them have chosen to have online shops."
n. 营养
Fair enough. Let's put the Kings in the “maybe” file. I'll drop the Nuggets in there, as well, as they are in basically the same place as a franchise, give or take some dysfunctional elements. The Wizards have to go in there, too, much as I am down on them at the moment.
可口可乐首席执行官穆泰康


比蒂和唐纳薇上台宣布最佳影片奖时,卡利南和瑞兹意识到他们手里还有两只最佳影片信封,也就是说,拿上台的信封是已经宣布过的奖项。
Winners: Lakers
Mr Koepke argues, however, that the role of US interest rates in provoking EM crises has not been fully understood. He presents evidence that the probability of EM crises is substantially higher during a conjunction of three conditions: during a Fed tightening cycle, when the federal funds rate is above its natural rate (the rate that leads actual output to converge to potential output), and when market participants are surprised by signals that the Fed will tighten policy faster than previously expected.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

Belgium and Uruguay are two diminutive countries that have maximized their advantages through inclusiveness, and of which Brazil, Argentina, Spain and Germany -- the quartet of forerunners for this year's title -- will rightly be wary. They, in the manner of Brazil's indigenous mosquitos and scorpions, are a useful reminder that small can often be deadly.
Company: Samasource
英国商学院在2015年英国《金融时报》欧洲商学院排行榜上大放异彩。不仅伦敦商学院(LBS)再次摘得欧洲最佳商学院的桂冠,还有其他3所英国商学院的排名取得了自去年以来的最大幅度上升。
年龄:31岁

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

美因何而存在?为了回答这个问题,鸟类学家理查德?O?普鲁姆正试图令达尔文的一种观点重新流行:同一个物种中,动物对其同类的吸引力,不仅仅与健康和良好的基因有关。动物,尤其是普鲁姆博士所研究的鸟类,会做出主观的决定。他希望进化生物学家不要再“为欲望辩解”了。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

1月,因本田未按要求向美国国家公路交通安全管理局汇报各类车辆上发生的1700多起伤亡事故,美国政府向该公司开具7000万美元的高额罚单。
赖特是英国浪漫主义画派的鼻祖之一。这幅作品从1840年起一直由德比郡的一个家族私藏。考虑到目前的行情,它的最低估价仅为10万英镑,还有一个重要因素是它的拍卖款将用于救济叙利亚难民。结果,至少有三位竞拍人把价格推高至66.5万英镑(含佣金)。

[.?ndi'nai?bl]
小牛队老板马克-库班曾下过比这更大的赌注,但是,他尝试换来诺埃尔作为空中接力/护框型球员——像泰森-钱德勒那样,舍弃的东西并不多(贾斯廷-安德森和一次伪第一轮选秀权)。
But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.
而诺贝尔物理学奖则颁给了三位生于英国、目前正在美国工作的科学家,肯定了他们对极端状态下物质的特异属性所做的原子级研究。
“我不知道发生了什么”洛瑞说。“我只知道我被吹罚了一次进攻犯规,就这么发生了。这就是NBA,这就是我想说的。”
Investigators have arrested one youth and one 18-year-old in connection to the July 9th shooting.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


新装修居室甲醛超标较为普遍 室内空气治理迎来千亿元市场


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


n. 匙,调羹,匙状物
新建的房产将给那些财大气粗的租房者提供奢华的居住选择,它们大多位于曼哈顿以外的行政区。根据花旗居屋的数据,在布鲁克林,预计有6527个新的出租单元,将于明年(2015年——译注)投放租赁市场,比曼哈顿3802个单元多出近一倍。
2012年中国网游市场将占全球半壁江山
Finance is one of top school Edhec’s core strengths, both in terms of teaching and research. The school in 2001 established the Edhec-Risk Institute to produce and distribute research on areas such as asset and risk management.
4.室外类比赛项目
[i'fektiv]
For a few years, Namibia's dollar has been depreciating against many currencies, providing affordable opportunities for travel. The best-priced flights generally avoid South African and European school-holiday times, especially late December and January.
不过,随着纽约人日益习惯于共享经济,各处楼盘可能最终也不得不接受它。
“这部电影讲述的是在荒野中求生存、适应自然以及人文精神的胜利,更重要的主题是信任。”
据当地媒体报道,这一犯罪团伙设在广西壮族自治区首府南宁,他们向腐肉中注射化学药品,使其增重50%,这样每吨腐肉便可获利16000元人民币(合1750英镑)。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the However, you know when your cycles are over when the washer and dryer stop making noise. And you know when the weather is ugly by simply looking outside, or checking your weather app. Therefore, the product is basically just another way hackers can get into your home. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

中国旅游研究院的蒋依依建议,中国政府应实行一项长期的国家计划,以提升国家形象并投资于入境旅游以吸引更多游客前来。
To Anita Eerland and Rolf Zwaan [THE NETHERLANDS] and Tulio Guadalupe [PERU, RUSSIA, and THE NETHERLANDS] for their study “Leaning to the Left Makes the Eiffel Tower Seem Smaller."
Top male vocalist: Jason Aldean
如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。

大小:3073平方英尺(约286平方米)

  • Only the first three authors are listed, followed by "et al."
  • 统计局:1-6月份全国房地产开发投资55531亿元 同比增9.7%
  • 北京工商海淀分局查处假冒建材722件


韦斯·安德森(Wes Anderson)的每部电影似乎都存在于它自己的世界里。《布达佩斯大饭店》(The Grand Budapest Hotel)以20世纪30年代为背景,通过独特的元素和道具定义它的世界。
随着威斯布鲁克成为一个事事亲为和高使用率的角色,奥拉迪波固定成为一个昂贵的补充品,佩恩需要证明他无球时的威胁力、或是能成为带动第二阵容的后卫,

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