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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

即使我们把吉布森视作租赁合同并且他将在夏天离开,雷霆对这笔交易依然感觉良好。
Much of the boost in exports came from shipments to the US, which grew for the first time since March at an annualised rate of 6.9 per cent to $36.8bn. Among other destinations that swung back to growth last month was the the EU, shipments to which rose 5.1 per cent to $29.9bn, as did those to Japan, by 3.2 per cent to $12.2bn.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

在气候学的史册里,2014年超过了2010年,成为最热的年份。有记录以来的10个最暖年份都是在1997年以后,反映了地球不断变暖的趋势,科学家说,这种变暖是人类活动的结果,并对人类文明和大自然构成了深远的长期危险。
Winners: Pelicans

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

设在日内瓦的国际移民组织星期二公布的数字显示,一百万零五千五百零四名非洲和中东的流动人口,以非常规方式通过陆路和海路进入欧洲大陆,这个数字是2014年的四倍。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 明年公租房有效供应将加大
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

The theory describes Type B individuals as a contrast to those of Type A. Type B personality, by definition, are noted to live at lower stress levels. They typically work steadily, and may enjoy achievement, although they have a greater tendency to disregard physical or mental stress when they do not achieve.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

While you're studying, pay attention to the material you know will be on a test and write a quick practice question. Start a new document on your laptop and add questions as you think of them.
但这种理念不会让英国退欧或者让特朗普当选总统。
作为本田的高端品牌,讴歌去年共售出167,843辆,同比微增1.5%。而在美国这一备受豪华车品牌青睐的市场上,丰田的高端品牌雷克萨斯销量增幅为13.7%,宝马增幅为9.8%,奥迪增幅为15.2%,梅赛德斯-奔驰增幅为6.5%。
赢家:鹈鹕

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

The most popular variation of this line is “Don’t fantasize about big sister: I am only legend.”
Much of the boost in exports came from shipments to the US, which grew for the first time since March at an annualised rate of 6.9 per cent to $36.8bn. Among other destinations that swung back to growth last month was the the EU, shipments to which rose 5.1 per cent to $29.9bn, as did those to Japan, by 3.2 per cent to $12.2bn.
潘通在解释这一选择时提到以下这些因素:“主张性别平等和流动性的社会运动;消费者越来越喜欢把色彩当作一种表达方式;这一代人不太在意被认定为某一种类型或遭到评判;公开的数字信息交流让我们看到颜色使用的不同方式。”
每到仲夏时节,这家企业数据存储公司就会通过举办“狗狗节”来提升士气。员工此时可带着自己的宠物上班,欣赏宠物商品展销会,当地的宠物美容师、宠物商店老板以及驯兽师都会参展,还可以观赏狗狗才艺表演。在“狗狗节”前一周会有一场彩票抽奖活动,全部收入都将捐献给当地的动物慈善机构。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

11月份以美元计算的中国出口和进口额都增加了,此前它们经历了两个月的收缩,而且这一增长是在上月美国总统选举后美元升值背景下实现的。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

And while you are at it, don't forget to celebrate the imperfections. While on a 10-day trek in the Himalayas, I learned that imperfections are beautiful too. The rough edges of the mountains, the heavy hail storms in the middle of the afternoon, were "inconvenient" but added to the beauty of the trek. I am acutely aware now that in my pursuit of perfection at work, I have often failed to recognize that imperfections are also a core part of our identity that needs to be preserved and not always changed.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

打造众创、众包、众扶、众筹平台
Chicago-based rival AT Kearney is also preparing for a change at the top, with a vote to replace Johan Aurik, who has already served the maximum two terms as managing partner, due to take place in the first quarter of 2018. His replacement will be expected to focus on how to pull AT Kearney out of the ranks of mid-sized players.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

周二在上海举办的中国国际机器人产业发展高峰论坛称,2017年,工业机器人的销量和增速均创新高。在这些工业机器人当中,有37825台为国产制造,同比增长29.8%。
“去年,有120万中国人来澳大利亚旅游,我们预计这将在中澳旅游年期间增长,并将继续增长。”

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 郑州首套房贷款利率上浮10%成主流
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Foreign robot makers sold 103,191 robots to China in 2017, up 71.9% from a year earlier.
Lecent Ross枪击案已逮捕两人

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在《醉乡民谣》(Inside Llewyn Davis)中,编剧兼导演乔尔?科恩(Joel Coen)和伊桑?科恩(Ethan Coen)兄弟俩挥之不去的忧伤情绪转化成了令人难忘的戏剧性场面。我觉得我的评论本应澄清,这部关于流行文化牺牲品的悲歌有一种特别的味道;其中一些部分相当阴郁。奥斯卡?伊萨克(Oscar Isaac)在片中出演一位自暴自弃的民谣乐手,宿命般地献身于他的艺术,他的卓越表演令这部影片极其震撼人心。
到目前为止雷神一直是漫威电影宇宙被遗忘的那个孩子。尽管有些人喜欢肯尼思?布莱纳执导的《雷神》第一部,但主演克里斯?海姆斯沃斯的风头显然被汤姆?希德勒斯顿饰演的自负反派洛基给盖过了。《雷神》第二部被公认为漫威有史以来最糟的电影。所以,为了给这个走下坡路的系列注入新活力,漫威在拍第三部时请来了新西兰喜剧电影导演泰卡瓦蒂蒂,给电影增加一些新西兰人的奇思妙想。这一次雷神要降服的对手是由凯特?布兰切特饰演的死神。雷神也许有锤子,但死神有气派。影片于11月1日在塞尔维亚和匈牙利上映,11月2日在柬埔寨和以色列上映,11月3日在印度和加拿大上映。(资料来源:漫威影业)
在世界五大电脑制造商中,苹果公司是去年唯一一家出货量保持增长的公司,涨幅超过了6%;宏碁公司则是下跌幅度最大,下跌超过了18%。
and the regime's first move—cashing in Lou Williams to the Rockets for a first-round pick—is a clear sign they realize that they must do everything to retain their own top-three protected pick in June's draft.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

One of the things that makes Guardians such a great superhero franchise is its sense of humor—which is full of self-deprecation and sarcasm. It's not like you're going to watch this movie and laugh your way through it, but you'll at least have some moments of "ha ha, Groot," and "lolololol Chris Pratt."

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 卫浴企业如何突破同质化“枷锁”
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

n. 部分,份,命运,分担的责任
赢家:猛龙

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

vi

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 人民日报:结构性去杠杆稳步推进
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

韩云平表示,去年全国的质量监督部门共提交了36000起和违反质量标准有关的案件,涉及金额达23亿人民币(约合3.33亿美元)的货物。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

vt. 作 ... 姿
Collins grew up in rural, apartheid-era South Africa in the 1970s. Her childhood inspired her to focus on empowering women living below the poverty line through grassroots efforts. The Wonderbag, which was inspired by watching her grandmother cook with cushions, uses heat retention technology to cook food for 8-12 hours without the need for additional fuel. Collins witnessed the benefits African women received from using Wonderbags, reducing the amount of time they spent collecting firewood. For every bag sold, another is donated to a household in Africa, and in the past four years, the Wonderbags have found themselves in 600,000 African homes. Collins has launched the Wonderbag in the U.S. on Amazon, and hopes to sell the products via other retailers by 2014.
I’m not saying you should blindly accept everything that’s offered to you, it’s okay to take time when considering the pros and cons of an opportunity. But, when you find yourself leaning toward “No,” you owe it to yourself to be sure that you’re turning down the opportunity for a valid reason, not just out of fear.
Define yourself

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

201007/109869.shtml
许多人在学习小组中受益良多。你得有条有理地进行,不能拖延时间。你要将学习的内容彻底消化,并能够向别人复述出来。
In reality, bitcoin displayed major momentum in the last year as both a technology and a movement, and looks poised to convert more skeptics in the year to come. The metrics in a range of areas prove it: the number of bitcoin-related startups and jobs has boomed; the number of accepting institutions has bloomed; and activity among developers is greater than ever.
established
公司:(Wonderbag)Natural Balance公司

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Some of these people have instead reached for issues that feel close to their concerns: trade, crime, the war on drugs, controlling the borders, fear of Islamist terrorism. All are significant in their own right, and create very real fears for many people, but they have also become a means to have a public conversation about what society’s changes mean for white majorities.
over $50,000 category, pickups and SUVs distributed through non-premium dealers outsell German luxury brands.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

有A型人格特征的人往往是高成就的“工作狂”。他们用最后期限激励自己,讨厌延迟和矛盾心理。A型人格的人工作压力更大,工作满意度更低。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

2013 Rank: 2

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

对于上周有媒体称三星和黑莓正在进行收购洽淡的报道,两家公司都迅速予以否认。但全球最大的智能手机厂商为何愿意付出传闻中的75亿美元高价,来收购一家盛年不再的加拿大技术公司呢?答案是:因为后者持有丰富的知识产权——尤其是在前景光明的安全创新领域。
Texas was one of the first states to emerge from the recession and it continues to attract companies on the basis of its low tax burden, predictable regulatory environment and skilled labor force. Texas employment is expected to expand 3% annually through 2017, according to Moody’s. (Arizona’s forecasted rate is a microscopic 0.04% better). Texas has attracted a lot of attention from California companies and Governor Rick Perry has not been shy about contrasting the business climates of the two states. California firms EBay and Electronic Arts have both chosen Texas for large expansions in recent years. Austin has been a hotbed of activity this year with Accenture
有人将一杯滚烫的咖啡洒在了求职者身上。
Notably, among the nine schools ranked for the first time, WP Carey School of Business at the Arizona State University is the first US institution to take part in the ranking, having entered at 82.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

我们在中高速行进当中也会系紧安全带,不会让风险“急性发作”,更不会发生区域性或者系统性的风险。
2017年,人们指责大型科技公司太过强大、利用自身的规模主宰市场,而且不够关注他们所创造的工具如何被用来做恶。
A robust LinkedIn presence is crucial to any job search. You know that. Your manager knows that. And your manager probably knows that you know that – so she'll be concerned when you go from having a bare-bones profile on Monday to one jacked with additional work history, new connections, status updates and recommendations by Friday. "Don't go from zero to 500 overnight, because that can be quite obvious," Foss cautions。
Ronaldo's monster pay-packet was the result of his eye-watering pound 38.5 million-a-year salary with Spanish giants Real Madrid and endorsement deals with the likes of Nike, watchmaker Tag Heuer and nutrition supplements group Herbalife - themselves worth pound 22 million.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Interestingly, BRICS bloc has reduced their exposure to these securities at a time when America's economic activity is expanding at a moderate rate.
Autonomous cars: Researchers are working on devices that will automatically park your car in a parking lot without you being in, or near, the car. It will also slip a note under the wipers of the car next to it with your phone number and insurance carrier in case of any scratches.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

昨日发布的新数据是对2015年全球贸易图景的第一张快照。但在这些数据发布之际,有越来越多的人担心2016年对全球经济而言将比此前预期的更为危机四伏。
It was the second weekend in a row that Venezuela's socialist government opened the long-closed border with Colombia and by 6 a.m. Sunday a line of would-be shoppers snaked through the entire town of San Antonio del Tachira. Some had traveled in chartered buses from cities 10 hours away.
adj. 迷人的
3. Jia Junpeng, your mom wants you to go home for dinner.”
Blue skies will not be, and should not be, a luxury.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

n. 疏忽,忽视
Did I mention that LeBron James is a free agent this summer?
Rank: 3

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

联系方式:Debbie McNally, Lakes Sotheby’s International Realty, (612) 388-1790; debbiemcnally.com
上月越南主席张晋创对中国进行国访,会见中国主席习近平。但中越双方并未就跨境贸易达成一致。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

8. Flats are allowed on the red carpet – or are they?
“有个员工把一块上面写着‘我不干了!’的砖头扔进公司窗户。”
上榜的12所美国学院平均而言是性别比例最为平衡的,女性学员比例为48%。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

But that recovery has also seen the size of bonuses drop: last year the average payout was Rmb12,821 ($1,861), about Rmb2,000 more than in 2015 but still roughly Rmb800 below the 2014 average. More than a quarter of those surveyed who saw their bonus shrink last year blamed the decrease on poor company performance.
下面是今年最令人难忘的四个设计,包括参与塑造这些造型的一些艺术家们的评论。
据张晓光表示,怀旧部分将包括出自上海文华电影制作工作室的电影,该公司成立于1946年、引领了中国文艺电影的新时代,将会让观众“一睹中国的电影文化和历史”。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 乌兰察布着力打造建材产业集群
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

改编自上世纪70年代真实贿赂事件的影片《美国骗局》当晚表现更加抢眼,埃米?亚当斯(Amy Adams)和珍妮弗?劳伦斯(Jennifer Lawrence)凭此片分获最佳女主角和最佳女配角奖。《为奴十二年》虽在提名数量上与《美国骗局》打平,参与了七个奖项的角逐,但当晚只摘得最佳剧情片一个奖项。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

2. Get a Belstaff coat and blue scarf. The coat cost about 1350 pounds. It's got good twirl for those dramatic moments in life.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

对于在泥潭里挣扎的球队,有一样建队过程中关键的东西一直诱惑着他们,那就是建队计划。
5. 格罗斯警告:“庞氏骗局!临界点!信贷超新星!”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
From the themed collection: 别以为披着网红马甲就不是黑旅舍
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

挪威诺贝尔和平奖委员会表示,希望这次的颁奖有助于制止在很多国家内仍然存在的对女性的压迫。
[.n?vi'gein]
中国民航局局长冯正霖表示,因天气造成航班延误的比例由2015年的29.5%增至2016年的56.8%。
国际美容整形外科学会发布的数据显示,若考虑人口因素,韩国现在是全世界整形美容业最大的市场。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

The tightening drove some enterprises seek other financing options such as bonds or listing on the National Equities Exchange and Quotations (NEEQ).
高恩洛夫罗列出一长串有关2014年的坏消息:“2013年一季度GDP年化增长速度为1.8%……向下修正了早前增长2.4%的估计……一季度的惨淡增长至少好于2012年四季度GDP 0.4%的增长,但离健康的增长仍然差了很多,经济学家预计短时间内也不会好到哪里去。”对进入2014年的市场来说,这是实打实的坏消息。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

“白”之禁忌
Quite a few students were disillusioned by UK visa regulations. “A lot of people saw the programme as a gateway to employment in Europe,” says one. “If this was the objective, then a lot of them would have gone away unfulfilled.”

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 深圳十部门联手整治楼市乱象
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

I, however, am not among them.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 北京大兴区富强路有违建楼上楼
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

It is the thirdhighest overall behind the two Indian management academies at Ahmedabad and Bangalore, with respective salaries of $109,000 and $106,000.
16. 最受忽视的真相。“这个行业内有一个神话,就是年轻男性主导着票房,”11月,索尼电影娱乐公司电影组主席汤姆·罗斯曼(Tom Rothman)在接受《好莱坞报道者》(Hollywood Reporter)采访时说。在同一次采访中,沃尔特·迪士尼公司的主席艾伦·F·霍恩(Alan F. Horn)试图把问题简化,“演员薪酬受很多变量影响。比如说,安吉丽娜·朱莉出演《沉睡魔咒》(Maleficent)的片酬就比黛西·雷德利(Daisy Ridley)出演《星球大战》(Star Wars)高,但她们都是女性。”(哦,多谢了艾伦!)
2. Worldwide Murders
n. 光泽,上光剂,优雅,精良

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

['pr?uti:n]
Snapchat on Tuesday launched Discover, a section of its app where media outlets including Vice, CNN andPeople magazine can publish video content within Snapchat. Already several of the channels feature ads, which aren’t cheap. According to Adweek, Snapchat ads cost $750,000 per day.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Children show “Paper-cutting Flowers” (China Southern Dance School under the China Dancers Association)
亚洲的商界女性在崛起:整个亚洲地区在榜单上的表现都非常抢眼,从中国和新加坡到新西兰和泰国,都能找到女强人的身影。亚洲的女性企业家群体正在崛起,例如张欣(排名第50)、孙亚芳(排名第77)和周凯旋(排名第80)。在政界,亚洲女性也在施展自己的抱负,例如新上榜的韩国总统朴槿惠(排名第11),缅甸反对派领袖、国会议员昂山素季(排名第29),澳大利亚总理茱莉亚·杰拉德(排名第28),以及泰国总理英拉·西那瓦(排名第31)。
而至于他自己的教育问题:他在考虑是留在英国,还是为了离硅谷更近而去读美国的大学。再或者,他也许会放弃学业,全然专注于他的事业。他说,我非常想再创办一家公司,连续创业家们都是对创新上瘾的人。我希望能保有热情。如果我不能尝试新的事物,我会感觉很糟。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Between 2015 and 2016, the US market grew by 20 per cent, while the Asian market increased by just 10 per cent. There are two ways to look at the relatively modest size of the Asian ETF market compared with both the US and Europe — which is twice as big as Asia, with $716bn in ETF assets — say analysts.
Fudan University and Peking University, two prestigious comprehensive universities in China, were ranked fourth and sixth on the salary ranking, while the remaining of the top 20 were dominated by finance/economics and science/technology schools.
Falke的最终失利令人扼腕,但eBay的表现确实无可匹敌。我以为自己对eBay的爱将矢志不渝,因为鄙人全部的穿戴和家中物件均来自这家公司,而它却向《纽约时报》(the New York Times)表示:“我们热切希望利用我们的平台,通过营造公平的竞争环境来造福数百万人。”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Gitanjali said she wanted to further refine the device so it could eventually go on the market.
Horowitz, speaking to radio station RTE, said he was keen to keep the new Bond true to the 1950s creation.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 宁波家装建材质量抽检合格率仅73%
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

就在一个月前,近200个国家的政府在巴黎达成了一项新的气候协议,目标是阻止全球气温比工业化前水平上升2摄氏度以上,最好限制在1.5摄氏度以内。
China's Internet celebrities are estimated to create a whopping 58 billion yuan ($8.7 billion) market in 2016, far surpassing the 44 billion yuan in box office sales generated last year, according to an industry report.
For almost everyone else, it was a year of frustration against a backdrop of better-than-average returns for the most popular index in the land.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

And, thanks to Artnet and other databases that list auction results, wealthy people who buy art have become all too aware of how hard it is to make a profit on old masters.
单词administration 联想记忆:

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

adj. 复杂的,复合的,合成的
很多明星获得的小金人都被放在了父母身边,安吉丽娜·朱莉(Angeline Jolie)已故的母亲多年来一直保存着女儿因影片《女生向前走》(Girl)获得的最佳女配角奖杯。妮可·基德曼(Nicole Kidman)因影片《时时刻刻》(《The Hours》)获得了最佳女主角奖,奖杯就放在她父母家中的壁炉台上,来串门的邻居都可以看到。詹妮弗·劳伦斯(Jennifer Lawrence)于2013年凭借《乌云背后的幸福线》(Silver Linings Playbook)获得第85届奥斯卡最佳女主角,奖杯放在她父母家中的钢琴上。
中欧之间存在贸易摩擦,我们有经验去妥善解决。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

已经60岁的微软老大净资产达到750亿美元,尽管比起2015年缩水了42亿美元,却仍足以傲视群雄。自2014年超越墨西哥首富卡洛斯·斯利姆·埃卢以来,盖茨实现了福布斯富豪榜榜首三连庄。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

n. 无限
一位本田高管私下里将该公司的很多问题归咎于“运气不好”,而不是内部管理不当或有意失职。也许确实如此。不过本田管理层确实应该认真反省,反复自查,并控制好其管理系统和生产流程,确保客户好感度不再每况愈下。(财富中文网)

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 上半年全国陶瓷出口数据公布
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

adj.
9. “The Big Short” Adam McKay plays it for comedy, but as he carpet-bombs the screen with laughs, he makes it clear that his take on the 2008 economic meltdown is a staggering American tragedy.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The ranking is based on surveys of schools and alumni who graduated in2011. This edition gives a snapshot of alumni’s situation compared with when they started the programme.
Her mother discovered the debits on Jan 30, China Central Television reported.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

All but one of the other top 10 categories reflected public fascination with celebrities. Teen pop sensation Miley Cyrus was in third place in the search rankings and television personality Kim Kardashianwas not far behind at fourth place. They were followed by Lady Gaga at No. 5, actress Megan Fox in seventh place, with Justin Bieber, American Idol and Britney Spears completing the top 10. The iPhone stood out as the exception, coming in sixth.
Maddie has now appeared in three of Sia's videos - Chandelier, Elastic Heart and Big Girls Cry.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

《出生于缅甸皇室的她成为军阀和大毒枭》(The Female Warlord Who Had C.I.A. Connections and Opium Routes)

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

是的,这经常发生。你可以在家里,图书馆,打印店等除了你现在工作的公司办公室的任何地方打印申请材料。
2015年英国《金融时报》全球高管工商管理硕士课程(Global Executive MBA,简称全球EMBA)排行榜由于两个原因而引人注目。不仅因为这是英国《金融时报》发布的第100个商学院排行榜,也是因为今年首次有一个主办方包含一所中国内地商学院的项目拔得头筹。
偶尔关心他们一下,但也别太真情流露,收到?
n. 信用,荣誉,贷款,学分,赞扬,赊欠,贷方

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

You're talking with him / her late on the phone. When he / she hung up the phone, you still miss him / her, even if the phone just hung up on 2 minutes

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 2016,家具行业大事件年终盘点!
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

罗杰斯对于中间剧情的反转十分不满,因此在拍完前三季之后决定离开剧组。这样的违约行为使他面临数百万美元的诉讼。但讽刺的是,韦恩·罗杰斯从来没有正式和剧组签订过合同(他涉及道德条款方面的问题)。因此该诉讼请求被驳回。你可能会说在这次的事件中,罗杰斯是笑到最后的人,但自从他离开剧组,《风流医生俏护士》又播出了八季,而罗杰斯在他的演艺生涯中再也没有取得过这样的成就。所以说他是笑到最后的人,也许只是一个相对的说法。
上个月,中国贸易顺差增至4962亿元人民币,高于去年12月的3821亿元人民币。经济学家曾预计该数据将略高于3890亿元人民币。以美元计,该月中国贸易顺差从去年12月的600.9亿美元增至632.9亿美元,也超过了606亿美元的预期。
迪皮卡 帕度柯妮

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

8Australia
上榜理由:探险之旅

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

单词creative 联想记忆:
According to the announcement, the new administrative center in Tongzhou will put infrastructure upgrades and ecological improvement on top of the agenda. The municipal government hopes to improve public services in education, healthcare, cultural events and industries in the district.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 大兴通州两商办项目被暂停网签
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The Cnzz.com report also discusses the problem of the 'free-to-play' business model that's prevalent in China's online game sector. While many games companies in the U.S., for example, charge subscription fees, most Chinese games utilize the free-to-play model, which allows players to try out a game without paying. The longer players stay in the game, the more likely they will be to pay for in-game items to move up into higher levels of play. But that also means that people who spend the most money are the best performers.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

In response, Mr Wilders labelled Mr Rutte a liar, citing the prime minister’s broken pledge not to support a bailout of Greece during the 2012 election.
In this April 24, 1984, file photo, from left, Steve Jobs, chairman of Apple Computers, John Sculley, president and CEO, and Steve Wozniak, co-founder of Apple, unveil the new Apple IIc computer in San Francisco
尽管当下是一个全球性的经济环境,但仅有约20%的美国人会说第二门语言。Sixty Vocab的目标就是以其在线外语游戏改变这一现状。基于2000个单词相当于一门外语的六成精髓的假设,Sixty Vocab试图使学习必要词汇的过程变得有趣。这些在线游戏能教你在对话中最为常用的词汇,并辅以限制时间的规则——你在越短的时间内猜出单词,你就能越快地进入到下一个阶段。Sixty Vocab填补了你高中课程和昂贵外语学习项目之间的空白,为那些想要在早餐咖啡或通勤时间学习一门外语的人提供了一个独一无二的选择。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在作品中,她围绕这台机器创造了一整个世界:人类、带着大礼帽的鲸鱼和龙居住在其中。
“我去的每一个地方,都发现企业主对未来的需求量有一个很好的预期,” Gus Faucher PNC金融服务机构的资深经济学家称。“商人必须提高薪酬来吸引更多的劳动力或者保留原有的工人”。
The theory describes Type B individuals as a contrast to those of Type A. Type B personality, by definition, are noted to live at lower stress levels. They typically work steadily, and may enjoy achievement, although they have a greater tendency to disregard physical or mental stress when they do not achieve.
Fereston recalls when writer Jennifer Crittenden stopped him in the hallway after filming and asked him, 'Are you sure about this? Are you sure you're not ruining Julia Louis-Dreyfus' career?' Considering Dreyfus won an Emmy that same year, it's safe to say the dance was a good career move for the actress. And now to reminisce, here is Elaine doing her famous "Elaine Dance."

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Purchase products like magazine racks, shelves, and desk organizers that will keep your supplies and resources in order and close-at-hand. We love the File File, $24.95, at CB2.com (pictured above).
Such borrowing is predicated in part on the assumption that by decontextualizing a style you also strip it of any possible negative implications: military, dynastic, what have you. It becomes an aesthetic form that exists on its own terms, as opposed to one that symbolizes all sorts of complicated societal or political convulsions.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

而诺贝尔物理学奖则颁给了三位生于英国、目前正在美国工作的科学家,肯定了他们对极端状态下物质的特异属性所做的原子级研究。
那么,于汽车业而言,2015年又意味着什么?以下是一些有根据的猜测。
2.Batman vs Superman: Dawn of Justice

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 家居消费贷 你买账吗?
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据第三方市场情报公司IDC日前公布的数据显示,去年中国智能手机制造商华为、OPPO以及vivo的年出货量大增,使得三家企业都成为了世界前5大智能手机制造商。
克里斯托弗诺兰的这部二战题材电影可能就是最佳影片的领跑者。

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